Proton therapy for paediatric medulloblastoma

Proton therapy for paediatric medulloblastoma.

Radiation oncology has changed greatly in recent decades, driven mainly by technical advances in treatment planning and delivery. Proton radiation therapy is a further advance; however, it is more expensive than traditional photon therapy and its critics argue that its costs are not justifi ed. Proton therapy is distinct from traditional photon or x-ray-based therapy since the physical properti...

Proton beam therapy for medulloblastoma.

It is heartening to read a report of good functional outcomes following proton beam therapy in young patients with medulloblastoma, including the absence of many unpleasant side eff ects that can occur after conventional photon therapy. The authors quote UK research, which criticises the current proton therapy treatment policy of dividing the x-ray (photon) equivalent dose by 1·1. This is done ...

Proton beam therapy for medulloblastoma - Author's reply.

Postoperative radiotherapy for paediatric medulloblastoma.

www.thelancet.com/oncology Published online August 11, 2016 http://dx.doi.org/10.1016/S1470-2045(16)30390-4 1 The proportion of children with medulloblastoma receiving deferred postoperative radiotherapy more than tripled in the USA from 2004 to 2012, according to new research. Benjamin Kann (Yale University School of Medicine, New Haven, CT, USA) and colleagues examined the records of 816 pati...

Long-term toxic effects of proton radiotherapy for paediatric medulloblastoma: a phase 2 single-arm study.

BACKGROUND Compared with traditional photon radiotherapy, proton radiotherapy irradiates less normal tissue and might improve health outcomes associated with photon radiotherapy by reducing toxic effects to normal tissue. We did a trial to assess late complications, acute side-effects, and survival associated with proton radiotherapy in children with medulloblastoma. METHODS In this non-rando...